pentobarbital will lower the extent or impact of temsirolimus by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
As well quick administration might bring about respiratory depression, laryngospasm, apnea, or vasodilation with fall in blood pressure level
pentobarbital will minimize the extent or result of rolapitant by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Extensive-term coadministration of strong CYP3A4 inducers with rolapitant may perhaps appreciably lower rolapitant efficacy.
pentobarbital will lower the level or outcome of pioglitazone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Slight/Significance Not known.
Observe Closely (1)pentobarbital will decrease the level or impact of tadalafil by impacting hepatic/intestinal enzyme CYP3A4 metabolism.
Contraindications to pentobarbital use include prior hypersensitivity reactions to drug use or barbiturate class use. Barbiturates can induce hypersensitivity reactions by direct histamine launch or immunoglobulin E (IgE)–mediated mechanisms and may lead to anaphylaxis.
pentobarbital will decrease the level or influence of colchicine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
pentobarbital will minimize the level or influence of fentanyl by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Check Intently. Coadministration of fentanyl with CYP3A4 inducers could lead to your decrease in fentanyl plasma concentrations, not enough efficacy or, perhaps, growth of a withdrawal syndrome in a affected individual who may have created Bodily dependence to fentanyl.
This drug may possibly increase the metabolism of estradiol when administered concurrently; clients on oral contraceptives are becoming Expecting when concurrently treated with antiepileptic prescription drugs; propose an alternate contraceptive technique to Women of all ages using this drug
pentobarbital will minimize the level or outcome of clozapine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
pentobarbital will lessen the extent or influence of atazanavir by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Mysterious.
pentobarbital will reduce the level or impact of dexamethasone by affecting hepatic/intestinal more info enzyme CYP3A4 metabolism. Use Caution/Monitor.
pentobarbital will minimize the level or effect of darunavir by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
pentobarbital will lessen the extent or influence of finasteride by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Significance Unfamiliar.